Angiodema and Cannabis

Angiodema is swelling that is similar to hives, but the swelling is under the skin instead of on the surface. MedlinePlus: Angiodema definition.

Allergic angioedema: this child is unable to open his eyes due to the swelling.
Image credit; By James Heilman, MD (Own work)
[CC BY-SA 3.0 or GFDL ], via Wikimedia Commons

The first report of a cannabis product being associated with an "excellent clinical response" when used as a treatment for angiodema was recently published by researchers from Ben-Gurion University of the Negev, in Beersheba, Israel. Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis.
Frenkel A, Roy-Shapira A, Evgeni B, Leonid K, Borer A, Klein M.
Case Reports Immunol. 2015;2015:780824. doi: 10.1155/2015/780824. Epub 2015 Jul 16.
PMID: 26257969 | Full article from PubMedCentral

"The rate of attacks dropped from at least twice a month to nil, appeared again a week after cessation, and disappeared again when treatment was restarted. This course is consistent with Koch’s postulates for establishing causality: frequent attacks before treatment, no attacks during treatment, and recurrence after temporarily stopping treatment."

Further reading

Wikipedia: Angiodema.
ASCIA: Allergy.org.au
NICE : Angio-oedema and anaphylaxis

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