N-arachidonoyl-dopamine (NADA)

Molecular Formula: C₂₈H₄₁NO₃
Image credit: PubChem

NADA is an agonist of the CB1 receptor. Cannabinoid modulation of peripheral autonomic and sensory neurotransmission.
Ralevic V.
Eur J Pharmacol. 2003 Jul 4;472(1-2):1-21. Review.
PMID: 12860468

NADA is is an "endovanilloid". It also activates vanilloid VR₁ receptors (coexpressed with cannabinoid CB₁ receptors), which excites sensory nerves and causes release of sensory neurotransmitter. N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo.
Bisogno T, Melck D, Bobrov MYu, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V.
Biochem J. 2000 Nov 1;351 Pt 3:817-24.
PMID: 11042139

NADA is a potent endogenous cannabinoid and vanilloid receptor agonist, with no action at dopamine receptors. TOCRIS
Product Database.
NADA #1568

External links

ChemSpider #4445314
WikiPedia
ChEMBL #138921
IUPHAR/BPU #5545
ZINC04102443