Delta8-tetrahydrocannabinol (Δ8-THC)

Δ8-THC Image Source: Wiki
Molecular Formula: C21H30O2
Image credit: Wikipedia
Δ8-THC is an analogue of tetrahydrocannabinol (Δ9-THC) with antiemetic, anxiolytic, appetite-stimulating, analgesic, and neuroprotective properties.

Delta-8-tetrahydrocannabinol (Δ8-THC) binds to the cannabinoid G-protein coupled receptor CB1, located in the central nervous system; CB1 receptor activation inhibits adenyl cyclase, increases mitogen-activated protein kinase activities, modulates several potassium channel conductances and inhibits N- and P/Q-type Ca2+ channels. This agent exhibits a lower psychotropic potency than delta-9-tetrahydrocannabinol (Δ9-THC), the primary form of THC found in cannabis. Source Name: NCIt
Source ID: C61312_3227
Record Name: Delta-8-Tetrahydrocannabinol
URL: http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C61312
Description: National Cancer Institute Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.

Further reading

ChemIDplus #5957-75-5
ChemSpider #4479481
WikiPedia
ZINC #2039624
IUPHAR/BPS #2424

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