Delta9-tetrahydrocannabinol (Δ9-THC)

THC Image Source: Wikipedia
Molecular Formula: C21H30O2
Image credit: Wikipedia

Δ9-THC is a psychotropic cannabinoid.

Δ9-THC has been shown to be analgesic, Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside.
Rahn EJ, Hohmann AG.
Neurotherapeutics. 2009 Oct;6(4):713-37. doi: 10.1016/j.nurt.2009.08.002. Review.
PMID: 19789075
antiemetic, Review of cannabinoids and their antiemetic effectiveness.
Vincent BJ, McQuiston DJ, Einhorn LH, Nagy CM, Brames MJ.
Drugs. 1983 Feb;25 Suppl 1:52-62.
PMID: 6301800
anti-inflammatory Cannabinoids in the management of difficult to treat pain.
Russo EB.
Ther Clin Risk Manag. 2008 Feb;4(1):245-59.
PMID: 18728714
and a neuroprotective antioxidant. Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
A. J. Hampson, M. Grimaldi, J. Axelrod, D. Wink
Proc Natl Acad Sci U S A. 1998 July 7; 95(14): 8268–8273.

Additionally, Δ9-THC is bronchodilatory, Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects.
Tashkin DP, Reiss S, Shapiro BJ, Calvarese B, Olsen JL, Lodge JW.
Am Rev Respir Dis. 1977 Jan;115(1):57-65.
PMID: 319717
a muscle relaxant, Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology.
Koppel BS, Brust JC, Fife T, Bronstein J, Youssof S, Gronseth G, Gloss D.
Neurology. 2014 Apr 29;82(17):1556-63. doi: 10.1212/WNL.0000000000000363. Review.
PMID: 24778283
and reduces Alzheimer's symptoms. The potential therapeutic effects of THC on Alzheimer's disease.
Cao C, Li Y, Liu H, Bai G, Mayl J, Lin X, Sutherland K, Nabar N, Cai J.
J Alzheimers Dis. 2014;42(3):973-84. doi: 10.3233/JAD-140093.
PMID: 25024327

Further reading

ChemIDplus #1972-08-3
ChemSpider #15266
ChEMBL #465
ZINC #2039624

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