Delta9-tetrahydrocannabivarin (Δ9-THCV)

THCV Image Source: PubChem Molecular Formula: C₁₉H₂₆O₂
Image credit: PubChem

Δ9-THCV is the propyl homolog of Δ9-THC.

Δ9-THCV has been shown to be a CB₁ neutral antagonist at low doses, The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity.
Wargent ET, Zaibi MS, Silvestri C, Hislop DC, Stocker CJ, Stott CG, Guy GW, Duncan M, Di Marzo V, Cawthorne MA.
Nutr Diabetes. 2013 May 27;3:e68. doi: 10.1038/nutd.2013.9.
PMID: 23712280 and an agonist of CB₁ and CB₂, at high doses. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.
Pertwee RG.
Br J Pharmacol. 2008 Jan;153(2):199-215. Epub 2007 Sep 10. Review.
PMID: 17828291

Anti-convulsant, anti-inflammatory, analgaesic The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.
Bolognini D, Costa B, Maione S, Comelli F, Marini P, Di Marzo V, Parolaro D, Ross RA, Gauson LA, Cascio MG, Pertwee RG.
Br J Pharmacol. 2010 Jun;160(3):677-87. doi: 10.1111/j.1476-5381.2010.00756.x.
PMID: 20590571 and antioxidant Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's disease.
García C, Palomo-Garo C, García-Arencibia M, Ramos J, Pertwee R, Fernández-Ruiz J.
Br J Pharmacol. 2011 Aug;163(7):1495-506. doi: 10.1111/j.1476-5381.2011.01278.x.
PMID: 21323909 properties have all been shown to be present in Δ9-THCV.

Delta9-tetrahydrocannabivarin (Δ9-THCV)

Δ9-THCV is the propyl homolog of Δ9-THC.

Further reading